Red Mask

Rarity	Uncommon
Tier	S

What it does

At the start of each combat apply 1 Weak to ALL enemies — team-wide damage reduction.

Relic values are checked against game v0.111— Early Access balance can shift between patches.

Other relics in this tier

Builds that scale with it

Exhaust Block

Corruption + Dark Embrace + Barricade + Body Slam

Strength Scaling

Demon Form + Limit Break + Vulnerable package

Sly Discard

Sly cards + Prepared/Acrobatics + Adrenaline

Poison Stacking

Deadly Poison + Catalyst + Wraith Form

Doom Execute

Blight Strike + End of Days + Soul engine

Claw Zero-Cost

Claw + All for One + FTL

Star Burst

Alignment + Seven Stars + Astral Pulse

Deep-dive guides

advanced

Slay the Spire 2 Relic Synergy Guide: All 42 Relics by Family, S-Tier Combos and Detour Rules (v0.111 Beta)

Every one of the 42 relics in Slay the Spire 2 v0.111 sorted into functional families: economy, defense, draw, energy, damage and character-locked, with tier S and A analysis, multiplicative engine combos and rules for when a relic is worth rerouting your path.

25 min read

beginner

Slay the Spire 2 Gold Economy and Shop Strategy Guide: Removals, Relics and Budgets (v0.111 Beta)

How to spend gold in Slay the Spire 2: why card removal beats card buying, when to save for Membership Card and other shop relics, act-by-act budgets, event income, and economy under Ascension 6 Inflation.

14 min read

combat

Slay the Spire 2 Elite Strategy Guide: All 14 Elites, Kill Orders and When to Fight or Skip (v0.111 Beta)

Every elite in Slay the Spire 2 v0.111 broken down by act: HP totals, turn loops, kill orders and counter cards for Bygone Effigy through Mecha Knight, plus the HP window math for when hunting elites beats routing around them.

23 min read